That is part of why I liked New Vegas so much, they were just like “yeah you can kill Caesar in camp, go ahead, the story is now differerent and you don’t get these quests but oh well, your choice”
Kind of the flip of the question but far cry 5 was particularly infuriating when it came to bullshit plot devices that override the players choices/skills. The boss fights were rigged with fixed outcomes regardless of what you hit the boss with. The fact that you could hit an unarmored human in the head with a rpg and see the explosion but the game was just like “yeah but the story says he’s alive so he’s alive. Also he is about to wreck your shit for… reasons…” drove me crazy…