Final Fantasy Tactics Advanced had tons of missions that required items and gave items. Your inventory had a cap so once you reached it you needed to decide on which inventory items to dstroy to make space for new rewards, or leave the rewards behind.
There were so many repeating quests so those rewards were safe to destroy. But if you destroyed a required item from a one-time quest(i don’t think there was anything special to mark these one-time side-quests)… no 100% game for you.