On my case, i’m a male and i always play with the male character unless i got no option.
Hypothetically, if i happen to play for example, Plants VS Zombies Garden Warfare 2, i would always play as the Sunflower, yes, the doctor brainz it’s also there but i would prefer being on the plants side (Although things may vary).
An example of a game where i had to forcefully play as a Female Character is Cally Caves 2.
Out of that, i mainly avoid playing with female characters, mostly because i’m a honest person.