IDK, just because Microsoft has products in a variety of categories doesn’t pose problems in itself, the problem is when those products command a significant chunk of the market share to the point where they can control a big chunk of the market. From your list:
GitHub - problematic because it’s the biggest code hosting platform around, but on its own isn’t a big issue
Teams - doesn’t really dominate, and many orgs use Slack or something else for communication
Xbox and XGS - not an issue unless either dominates their respective markets; buying large publishers like Activision is a serious issue
Azure - they’re like second or third, so there should be a close watch to make sure there isn’t monopolistic behavior with integrations with GitHub, Xbox, etc
And so on. I don’t personally think they should be broken up, but acquisitions in sectors where they already have significant market share should be blocked.