Same, but realistically once you start heading towards the 500 mods range, it's almost impossible to get it working reliably.
At one point I had 200+ mods on skyrim, and the mod cycles and before/after conflicts on vortex looked like mandelas. I did enjoy 'completing' the vortex mod manager game. That's when it's 3AM, you're fed up, you give up trying to figure what's wrong, and just click randomly and uninstall/reinstall mods until vortex shuts up, and it somehow just works. Bit like winning the lottery.