I kind of stopped paying attention to side quests. In a lot of RPGs, I feel like they’re discrete, separate errands, and usually contained within the area where they’re given. BG3 side quests seem a lot more integrated, in the sense that I’ll often just happen along the next step in one as I pursue main quest. If not, then it may be because the next step is in the next Act. And some of them seem to be mutually exclusive.
Maybe because it’s my first play through, but I’m now in ‘if it happens, it happens’ mode, and I’m confident that there are enough opportunities for me to make different choices to have a substantially different experience next time.