I’m using multi monitors with mixed resolutions and a very old nvidia card (gtx 670).
The only problem I have is that if I put them to sleep, while autorandr or whatever gets me the resolutions and layout back, the app windows move around like crazy because they all wake up at different times, likely due to a mix of HDMI + DVI + DisplayPort connections.
Edit: I see now, this is only an issue when we are talking about vrr simultaneously.
Dragon Age 2 is a bit ooof. Excellent combat, but the story and especially the scenery… you revisit the same parts of town and the same dungeon over and over and over.
If we are going down this path, I’d actually recommend touching grass first (proverbially), before a sinking time and money into a professional. It’s an easy, non-committal step, that may do wonders.