Late to the thread, and you already have loads of suggestions, but Portal and Portal2 may help your partner with their spatial issues. I’ve heard that those are the games to use to introduce someone who doesn’t play videogames in general, but specifically FPS, to the media and basic controls that most of us gamers take for granted.
Also StarCraft 2 can be modded with MassRecall so you can go through the SC1 campaigns, more than just SC and Broodwars, in the SC2 engine, which makes them a bit easier and more satisfying. I think that would allow you to do co-op on the original single player campaigns.
I don’t have Sims 2, I have Sims 4, but I may have missed Sims 2. My old computer couldn’t open the epic games launcher, so I missed the first six or eight months of games.
The entire BioShock collection, Rogue Legacy, Pathfinder Kingmaker, XCOM 2, Yooka-Laylee and Y-L and the Impossible Lair, Several Warhammer games, Turnip Boy Commits Tax Evasion, Tiny Tina’s Assault on Dragon Keep, Star Wars Squadrons, Bridge Constructor: The Walking Dead, Fallout 1, 2, 3, NV, and Tactics, Guacamelee and Guacamelee 2, Homeworld 1&2 Remastered, KSP, and of course LAWN MOWING SIMULATOR!!!
Edit: I almost forgot PC Building Simulator with the IT Expansion!
On the one hand, they were fun back in the day. On the other, who the fuck is supposed to intuitively figure out that I need a plate of spaghetti to give the bouncer? He didn’t say he was hungry, there was no indication that he wanted food to let me pass, it was totally random in far too many cases.