ME2 is a good game in isolation, but I think it played a big part in getting Bioware where they are now.
ME2 saw them move far, far more into the action-RPG direction that was wildly popular at the time, with a narrative that was in retrospect just running in place (ME2 contributes effectively nothing towards the greater plot and zero major issues are introduced if it is excised from the trilogy). I feel the wild success ME2 saw after going in this direction caused Bioware to (a) double down on trend chasing, and (b) abandon one of their core strengths of strong, cohesive narratives. ME3 chased multiplayer shooter trends, DA:I and ME:A both chased open world RPG trends, Anthem chased the live service trend, and the first try at DA3 chased more live service stuff before Anthem launched to shit and they scrapped the whole thing to start over.
All while, of what I saw first hand (of those I played) or read about secondhand (of those I did not play) none of those games put any serious focus on Bioware’s bread&butter of well written narratives. ME3 in particular is a narrative mess, with two solid payoffs (Krogans + Geth-Quarians) and the rest being some of the worst writing I’ve seen in a major video game.
ME2 was great. ME2 also set Bioware on a doomed path.