To be fair, lots of American media has rebellious motifs, but its mostly merely product packaging and doesn't really reflect American society.
I lived in the US at one point and while repetition of various freedom themed polemics was extremely common (it initially got annoying, until I learned to simply filter it out), I didn't really find the whole thing convincing. It felt more like posturing.
That being said, there is a lot of American literature, cinema and art more generally that is truly non-comfortmist.
Vampire: The Masquerade - Bloodlines - probably the most cliche answer possible, but Troika really did build a game that took you to the world of vampires in LA in the early 2000s.
Arcanum - a fantasy world undergoing industrialization with technology being in direct conflict with magic.
UnderRail - A society stuck underground connected by tunnels between towns/cities and nodes. The writing (quests/characters) is not that great, but the world-building is top notch.
After some thinking, I decided to pursue a revival for PS2 emulation on Android devices. A little side note, I don’t use Android, I’ve been an iPhone user since I’d received my first phone, my intentions were for the community remaining in Aether, as well as the overall Android community given how AetherSX2 went down. I first tried by recruiting new developers but come to find out it’s not an easy task whatsoever. I did manage to recruit two developers to the initial project, but busy schedules and a lack of progress led to stagnation, so I put my ambitions on hold for the time being.
Interesting that one of the lead devs of a PS2 Android emulator uses an iPhone. Nothing wrong with that, just peculiar.